1+ day, 10+ hour ago   (72+ words) Hypoxia-inducible factor 1 alpha, or HIF1α, has long been celebrated as the master switch that allows cells to sense and survive low-oxygen conditions, a discovery that earned the 2019 Nobel Prize in Physiology or Medicine. In the intestine, this transcription factor is far…...

1+ day, 12+ hour ago   (55+ words) A blood test that could help clinicians diagnose autism spectrum disorder in toddlers has moved a significant step closer to real-world use, thanks to a new translational study published in the Annals of Biomedical Engineering. Researchers led by Juergen Hahn…...

1+ day, 13+ hour ago   (84+ words) Chronic kidney disease is one of the world’s most burdensome chronic conditions, a slow and often silent deterioration of renal function that affects hundreds of millions of people and frequently goes undetected until the damage is advanced. Staging the disease…...

1+ day, 14+ hour ago   (686+ words) For decades, the body mass index has served as the gatekeeper of obesity medicine, a single number dividing patients into categories of normal weight, overweight, and obese. Yet clinicians have long suspected that the scale tells only part of the…...

1+ day, 14+ hour ago   (746+ words) A new commentary published in the Journal of Cancer Research and Clinical Oncology is challenging how exceptional individual responses to an experimental multiple myeloma drug should be interpreted, warning that remarkable case reports can inadvertently obscure evidence that a treatment…...

1+ day, 14+ hour ago   (761+ words) For a child with cancer, the word surgery often conjures the most frightening image of treatment: long incisions, weeks of recovery, and the permanent toll of removing tissue from a small, still-growing body. A comprehensive new review published in Pediatric…...

1+ day, 16+ hour ago   (75+ words) For women living far from hospitals and support groups, a cancer diagnosis can feel like an isolation sentence stacked on top of a medical one. New research suggests that something as simple as writing about their deepest thoughts and feelings…...

1+ day, 17+ hour ago   (664+ words) Chronic hepatitis B remains one of the world’s most stubborn infectious diseases, affecting an estimated 283 million people and contributing to roughly 550,000 deaths each year through cirrhosis and hepatocellular carcinoma, the third leading cause of cancer-related mortality globally....

1+ day, 17+ hour ago   (92+ words) Parvovirus B19 is best known to most people, if it is known at all, as the cause of fifth disease, the mild childhood illness marked by the distinctive ‘slapped cheek’ rash. In healthy adults the virus typically produces little more than…...

1+ day, 18+ hour ago   (542+ words) Alzheimer’s disease has long been portrayed as a story written in the cortex, the wrinkled outer layer of the brain where memory and thought reside. But a new study published in Nature Communications suggests that the opening chapters of that…...