1+ day, 9+ hour ago   (69+ words) A centuries-old plant alkaloid best known for lowering blood sugar may have another, far more ambitious role: slowing the aging of the immune system itself. In a comprehensive review published in the journal Biogerontology, researchers from the Russian Clinical Research…...

1+ day, 10+ hour ago   (72+ words) Hypoxia-inducible factor 1 alpha, or HIF1α, has long been celebrated as the master switch that allows cells to sense and survive low-oxygen conditions, a discovery that earned the 2019 Nobel Prize in Physiology or Medicine. In the intestine, this transcription factor is far…...

1+ day, 11+ hour ago   (769+ words) Older adults undergoing cancer treatment face a hidden metabolic threat that has long slipped through the cracks of oncology care. Corticosteroids, which are woven into many chemotherapy regimens and supportive care protocols to suppress nausea, allergic reactions and immune-related toxicity,…...

1+ day, 11+ hour ago   (69+ words) Small-cell lung cancer has long been one of oncology’s most punishing adversaries. It grows with astonishing speed, spreads early, and presents a treatment paradox that has frustrated clinicians for decades: at diagnosis, tumors melt away under platinum-based chemotherapy, yet relapse…...

1+ day, 11+ hour ago   (55+ words) Dental implants have become one of the most predictable long-term solutions for tooth replacement, yet their success hinges on a deceptively simple biological event: the direct, functional connection between the implant surface and the surrounding jawbone, known as osseointegration. Titanium,…...

1+ day, 11+ hour ago   (704+ words) A sweeping analysis of more than 635,000 cancer patients in South Korea has delivered one of the clearest signals yet that what lies beneath the scale matters far more than the number itself....

1+ day, 12+ hour ago   (55+ words) Immunotherapy has transformed the outlook for people with advanced bladder and kidney cancer. Drugs known as immune checkpoint inhibitors, which block molecular brakes such as CTLA-4, PD-1 and PD-L1 to unleash the immune system against tumours, have dramatically improved long-term…...

1+ day, 12+ hour ago   (73+ words) Goat milk has quietly become one of the most valued functional foods in the global dairy market, prized for its distinctive protein profile, low allergenicity, and rich supply of bioactive compounds. Compared with cow milk, goat milk contains smaller fat…...

1+ day, 12+ hour ago   (53+ words) Triple-negative breast cancer is the form of the disease that clinicians fear most. Lacking the three molecular targets — the estrogen receptor, the progesterone receptor and the HER2 protein — that anchor modern targeted therapies, it leaves patients with fewer options and a…...

1+ day, 12+ hour ago   (582+ words) Exercise is one of the most powerful medicines for the heart, enlarging cardiomyocytes in a healthy way and shielding the organ from the devastating damage that follows a heart attack. Yet the molecular arithmetic behind this benefit has remained stubbornly…...