1+ day, 1+ hour ago  (571+ words) Findings from a new study at Mount Sinai suggests radiotherapy alters the tumour environment to support CAR T cell persistence via dendritic cells, potentially overcoming a key challenge in solid tumours. Researchers at the Icahn School of Medicine at Mount…...

22+ hour, 24+ min ago  (687+ words) A team of international researchers have identified how breast cancer cells remain dormant in bone marrow for years, revealing a key role for Notch2 signalling in helping them evade treatment. Treating breast cancer is challenging due to the fact that cancer…...

1+ day, 1+ hour ago  (394+ words) The not-for-profit organisation has revealed the keynote programme for its flagship London conference, featuring Life Arc CEO Dr Sam Barrell CBE and a panel of senior industry leaders." ELRIG has announced the keynote speaker programme for their Drug Discovery 2026 conference,…...

1+ week, 6+ day ago  (474+ words) Scientists are exploring ferroptosis " a form of iron-dependent cell death " as a novel strategy to combat treatment resistance in digestive cancers which could provide new therapies for pancreatic, liver, colorectal and gastric malignancies that have proven resistant to conventional treatments....

1+ week, 6+ day ago  (425+ words) Researchers at Thomas Jefferson University have found evidence that senolytic therapies may help delay early intervertebral disc degeneration, a leading cause of chronic back and neck pain. Intervertebral disc degeneration affects millions of people worldwide and is a major contributor…...

1+ week, 6+ day ago  (524+ words) Shanghai researchers have developed a 13-gene chromosomal instability score that predicts breast cancer survival and identifies patients likely to respond to immunotherapy." Researchers at Renji Hospital, School of Medicine at"Shanghai Jiao Tong University have developed a new gene-based scoring…...

1+ week, 2+ hour ago  (381+ words) Traditional preclinical models are struggling to keep pace with a new generation of targeted therapies. As regulators embrace new approach methodologies (NAMs), vascularised tissue platforms are offering a more human-relevant approach to predicting drug efficacy and safety. These are not…...

1+ week, 5+ day ago  (383+ words) The new platform, known as Herb Syner_Finder, was created by a research team led by Professor Yinyin Wang and Professor Ninghua Tan. The system is designed to tackle one of the biggest challenges in herbal medicine research: identifying beneficial ingredient combinations…...

2+ week, 3+ hour ago  (1044+ words) Researchers at Phenomix Sciences are using machine learning and genetic risk scoring to investigate emotional hunger, an obesity phenotype linked to emotional and reward-driven eating behaviours. Dr Timothy O'Connor discusses how the approach could improve patient stratification, obesity research and…...

1+ week, 5+ day ago  (11+ words) Drug Target Review...